Russell Jaffe, MD, PhD, CCN
Thriving in the 21st century with Russell Jaffe, MD, PhD, CCN
Aired On: March 7, 2025
Show Notes
After reviewing over 100,000 lab values, 5000 biomarkers and epigenetics, he explored which biomarkers were predictive of optimal health and longevity.. He also has recommendations on how to improve each of these markers which improves and individual’s health trajectory. These biomarkers are:
Hemoglobin A 1 C (HbA1c) should be less than 5 %
- This is a measure of glycation (sugar stuck to hemoglobin) within the body within the body.
- Fructosamine is a back up measure if red blood cells are destroyed quickly (e.g. By immune conditions)
- If it is less than 5, you have a 99 % chance of living ten more years
HsCRP. High sensitivity C reactive protein should be less than .5
- This is a measure of inflammation
Homocysteine should be less than 6
- An all mortality marker
- This has a high correlation with all chronic diseases and is affected by methlation which is improved with folate and B vitamins
Vitamin D levels
- This is correlated with the risks for chronic diseases including covid
8 oxy guanine a test of DNA damage and oxidative damage (less than 5)
Omega 3 index should be greater than 8
Digestive Transit time should be less than 18 to 24 hours
- This measures time from eating food til it reaches the toilet. If this is too long, toxic components can be reabsorbed. If it is too short, nutrients may not be absorbed. It can be measured by taking charcoal and measuring the time until it reaches the toilet
Morning Urine PH should be between 6.5 and 7.5
- A measure of the body’s alkalinity/ acidity

Russell Jaffe, MD, PhD, CCN
Dr. Russell Jaffe received his BS, MD and PhD from the Boston University School of Medicine i1972. He completed residency training in clinical chemistry at the National Institutes of Health
(1973 – 1976), remaining on the permanent senior staff until 1979. He is board certified in Clinical Pathology and in Chemical Pathology. As a physician and scientist who aspired to be comprehensive, objective, empiric and experiential, Dr. Jaffe started his career searching for deeper understanding, wisdom, evidence and insight in mechanisms of health. Through intense curiosity and learned skepticism, Dr. Jaffe sought to debunk the best-known advocates of a variety of health promotion and healing systems. What started as a journey to disprove holistic forms of care became a rich educational experience that transformed Dr. Jaffe into a student and then researcher in such areas a Traditional Chinese Medicine, acupuncture, active meditation, homeopathy, and manipulative arts.
Russell Jaffe, MD, PhD
Website. www.DrRussellJaffe.com
Youtube channel:DrRussellJaffe
Books:
They Joy of Living the Alkaline way
Thriving in the 21 st Century
BhanteDharmawara: CambodianMonk Extraordinaire
- 92 % of your daily health is due to life style living
- The other 8 % is transgenerational influences and genetics
- Transgenerational influences are habits learned early: may have been passed down
His approach
- Reduce toxic burden
- Enhance body’s ability to get rid of remaining toxins
- You can decrease your body’s exposure to toxins by 80 %
- Have healthy digestive transit time
- Use bio-detoxifiers
- Exposure to toxins (Microplastics, glyphosate, DDT, DBE, PBF, PBA) has increased
- We can enhance our bodies’ ability to detoxify
- Garlic, Ginger, Red onions and Shallots, Brassica, broccoli sprouts, Duck or Quail eggs (“GGOBE”)
- White and yellow onions are too intoxicated
- He recommends avoiding highly intoxicating foods such as cow dairy, chicken and chicken eggs
- Avoid grains and have lots of grasses (improve microbiome and digestion)
- All grains have different glutens; oats have their own gluten, glyphosate and pesticide residues
- He recommends grasses such as millet, buckwheat, amaranth and quinoa, bamboo shoots
- Easy to digest, improve the microbiome, strengthen intestinal wall
- A weak leaky gut allows undigested food to enter the blood stream becoming immune burdens
- Peyer’s patches line the intestinal walls
- Half of Peyer’spatches defend the body by trapping partially digested remnants getting through leaky gut
- If the body is burdened with partially digested remnants or toxins, there is too much energy devoted to defense, there is not enough energy devoted to repair leading to inflammation
- Inflammation/ inflammo-aging indicates a “repair deficit”
- Therefore, reduce toxic burden and stimulate repair mechanisms.
- Garlic, Ginger, Red onions and Shallots, Brassica, broccoli sprouts, Duck or Quail eggs (“GGOBE”)
Diabetes
- Toxins and nutrients are important; fats are not important
Toxins
- Oxidative anti nutrients that deplete the body of essential nutrients
- Toxins are synergistic and affect the body through different mechanims
- They increase the need for good nutrients that they are depleting
- Want to enhance liver, kidney, spleen, heart, lungs, skin to get rid ot the 20 % toxins by supporting adaptogenicallybiology
- This addresses causes not symptoms of diseases
- Recommends
- Eat nothing in plastic
- When heavy metals are seen in the blood, it is already too late; it is already damaging the mind and the body
His most recent book
- Cambodian Buddhistmonk who taught him a noninvasive healing system
- He studied under this monk for 30 years during his ages between 80 and 110
- Colour healings
- He discusses the healing properties of greenlight 20 – 30 minutes while doing a mindfulness practice
- Green light stimulates harmony in pineal gland
- Recommends a dicromatic bulb or
- An LED green light that has multiple wavelengths The green chroma 520 to 540 nanometers.
- Phillips makes a specific LED with multiple wavelengths sold for comfort and clarity (cf. DrRussellJaffe.com and look up green light therapy)
- Blue light suppresses the pineal gland
- Computers and I phones emit blue light
- He discusses the healing properties of greenlight 20 – 30 minutes while doing a mindfulness practice
- Mind-body-sprit in harmony
- The pineal is the mistress of the master gland, the pituitary
- The pineal gland tells the pituitary gland what to send to the body to stimulate every cell in the immune defense and repair system to go to every cell in the body and identify warn out cells and cancer cells and eliminate them by apoptosis.
- This is innate physiology before pharmacology
- When you treat the body with respect, it responds with respect
- When you treat the body with toxins, the body deteriorates
- Prayer, relaxation response, mindfulness based meditation are all fine
- 20 minutes daily accumulates benefits to the body and the brain
- He finds abdominal deep breathing under a green light is sufficient
- Do whatever you enjoy doing
- Cortisol
- Shuts down the repair system, promotes inflammation and repair deficit
- Should be tamed and have a certain rhytym
- It should be higher in the morning and lower in the evening
- Measure at four different time points
- Balance with DHEA
- Cortisol and DHEA going up together is OK
- If Cortisol goes up and DHEa stays low, that is a problem
His paradigm shift towards health and primary prevention
- He investigated over 100,000 lab testsand investigate the effects of epigenetics, lifestyle and all the things we can influence
- This protocol will save over one million lives per year and over one trillion dollars in health/sick care.
- He recommends tests to do on ourselves, then will say how to interpret the results and what to do to improve what the test outcome measures
- Hemoglobin A1c (HbA1c)
- measures the average amount of sugar stuck to protein (hemoglobin)
- he does not measure insulin or serum glucose levels
- AGE (age related glycation end products) which cause atherosclerosis, coronary artery disease, heart disease, and stroke.
- This assumes a normal life span for red blood cells. If you are destroying red blood cells too quickly, use fructosamine
- should be less than 5 %
- If HbA1c is less than 5 %, you have a 99 % chance of living another ten years
- If HbA1c is 7% or 8 %, there is a dramatic decrease in duration and quality of life
- for support
- all sugars and sweetened beverages should be avoided. Added sugar and artificial sweeteners promote harm
- The sugar in fruits and vegetables is balanced by the fiber
- Eat whole foods: berries, vegetables, melons, sea vegetables, seeds, nuts
- Avoid ultra processedfoods
- Are fiber and nutrient deficient
- Contain preservatives, chemicals and additives to prolong the sehlf life and cause us to crave the particular food
- Food companies no identify themselves as packaged goods companies
- hsCRPhs C reactive protein
- should be less than 0.5
- measures inflammation and repair deficit
- homocysteine
- all mortality marker
- should be less than 6
- vitamin D
- should be between 50 and 80, this reduces the risk of chronicdisease
- take 5 to 10 drops daily under the tongue to get vitamin D levels in normal range
- Average levels in US (10 – 20) increases risk for chronic diseases, such as cardiorespiratory disease, cardio renal disease, cancer, autoimmunity,
- impaired digestion decreases vitamin Dabsorption
- urine testOxidative damage to DNA
- Support
- Nourish with anti-oxidants, ascorbate, magnesium, buffering minerals, omega three fats and essential nutrients to repair our DNA
- Support
- Omega 3 Index
- Available through Omega Quant lab
- should be more than 8 %
- omega 3 (DHA, EPA ) stimulates repair
- omega 6 stimulates reaction
- for example to eliminate a worn out cell
- too much omega 6 stimulates autoimmunity (self attack)
- it stimulates arthritis and diabetes, multiple sclerosis and all chronic inflammatory diseases
- every part of the body has a self attackingcomponent
- NHANES data confirms that most people get 30-60 times as much omega 6 than omega 3
- Fish oils
- Most fish oil is contaminated and is toxic
- Most of the EPA/DHA has been damaged by oxygen in the air
- Fish oil needs to be distilled under nitrogen to protect the EPA /DHA from damage and to remove toxins from the oil
- Then they microlyze into a soft gel
- This does not cause reflux
- The toxins and solvents in fish oil cause the fish oil to regurgitate
- Fish are contaminated. In the fish shop, the fish’s eyes should be clear
- If the eyes are cloudy, the fish has been frozen and thawed and probably exposed to biocides and harmfulchemicals
- Ask in the market which fish have been line caught and never have been frozen.
- Mercury in urine will be high within one week of eating fish
- Don’t eat fish within a week of heavy metals testing
- Digestive transit time (12- 18 hours)
- The average American has a digestive transit time of three to seven days
- If the digestive transit time is too long, harmful chemcials are created and reabsorbed back into the body
- Test with beets, or 6 to 12 charcoal tablets charcoal capsules
- microbiome should be attended to
- Stomach digestion is overlooked
- If the stomach does not start the digestive process properly, the small and large intestines, and rectum transit time increases
His final points
- Use nature, nurture and wholeness
- He believes in personalized primary prevention
- He wants to educate the consumer
- Be well hydrated. Start every meal with something wet and warm including three drops of Dr. Jaffe’s digestive aide
- 4 quarts liquid per day
- Should pee every two hours while awake
- 1 % or 2 % dehydration impairs everything from perception and productivity, restorative sleep, digestion, detoxification, and organ function
- Eat low on the food chain: organic or biodynamic uncontaminated foods
- Then the microbiome improves
- Once a week have
- a multibeam chili with organic or biodynamic spices
- a lentil dahl
- a curry
- a liquid nutrient day
- mushrooms, fungi, and sea vegetables
- sea vegetables provide essential ingredients (iodine)
- something unusual
- meast should be 100 % grass fed; never fed grains, corn or standard feed which fattens up the animal and gives the consumer fatty liver disease
- non alcohol fatty liver disease is relatively new disease