Infections: An Important Contribution to Autoimmunity Disease

Date Aired: August 25, 2017

Episode Description

Occult infections are risk factors for various diseases including heart disease and autoimmune disease. Bacterial, viral and parasite infections may be major contributors to autoimmune disease. In this program you will learn how to identify occult infections, to identify which infections are feeling autoimmune diseases and how to minimise the adverse effects of these infections.

I. AUTOIMMUNE DISEASES

  • Arise from inappropriate immune responses
  • In autoimmune diseases the body’s antibodies attack a part of the body by mistake
  • There are over 800 autoimmune diseases including multiple sclerosis (MS), lupus, rheumatoid arthritis, psoriasis, celiac, Hashimoto’s Disease, type I diabetes, sjogren’ disease, sarcoidosis, scleroderma, and possibly heart disease
  • Autoimmune diseases could be number one cause of morbidity and mortality
  • The age of onset is decreasing

II. REASONS FOR INCREASING AUTOIMMUNE DISEASES

  • Environmental toxins
    • There are 80,000 toxins in the planet
    • 200,000 toxins have been identified in Europe
    • Infectious agents can be toxic. These agents adapt and survive
    • Toxins bind to proteins, are seen as foreign, and the body generates antibodies against this complex (toxins with protein)
    • Plastic, heavy metal, food dyes , microbes can set off autoimmune process
  • Antibiotics
    • affect gut integrity and can increase the risks for autoimmune disease
    • one course antibiotics can affect health for the rest of our lives
  • Stress
    • Diminished host immune system due to stress
    • The word “stress” comes rail road girders bending
  • Poor Sleep
    • Decreased sleep leads to increased sympathetic stress.

III.     WHY WOMEN HAVE MORE AUTOIMMUNE DISEASES THAN MEN?

  • Women get eight times the number of autoimmune diseases than men
  • Haynes believes the difference is not due to hormones/ estrogen
  • He believes rheumatoid arthritis can be due to hidden infections in the urinary tract.
  • Bacteria in our gut influenced by testosterone which protects bacteria
  • Some gut bacteria can make more testosterone which is also protective effect against autoimmune disease
  • Acute and chronic immune responses differ in men and women
    • Men have acute reaction and passes
    • Women immune response more chronic low grade over time.
    • Women may not know they have the infection
  • He gives natural remedies

VI. CAUSES OF AUTOIMMUNITY DISEASE  NEED

A. Genetic susceptibility

B. Barrier permeability

  • need bad barrier integrity
    • intestines
    • blood brain barrier
    • skin
    • lungs

C. environmental trigger

  • foreign protein in the body
    • gluten most common
    • we react to different parts of gluten molecule and make antibodies against these parts –so we need to measure for these eight parts
    • These antibodies made against foreign proteins which also resemble tissues in body.   Hence through4  the process of molecular mimicry, the antibodies our bodies make mistakenly attacks the similar body tissue.
  • toxins bond to tissue which also presents as a foreign
    • (Cyrex Labs is testing this)
  • protein
  • infections (bacteria or virus)
    • He believes that hidden infections are the greatest contributor to autoimmune diseases
  1. the bacteria or virus presents itself to the immune system as a foreign entity and antibodies are made against it.
  2. The bacteria or virus can be very similar to tissues in the body.
  3. The immune system does what it is supposed to do have an immune response to that particular sequence.(antigen/ epitote)
  4. The immune system makes a mistake and attacks the parts of the body that are genetically similar to the virus or bacteria.
  5. Through molecular mimicry, body tissues may be attacked as a result of the infection.
  6. Hidden infections may be a bigger contributor to autoimmune diseases than toxins
  • Examples
    1. Proteus mirabilis antigen damage in Rh A

D. Environmental Stress

V. INFECTIONS AND AUTOIMMUNITY DISEASE

  • When he was a child, he went to measles, mumps, chicken pox parties so all the children could catch these diseases.

 

  • Alan Ebringer at Kings College, London spent 35 years studying the

connections between autoimmunity disease and infections. He found:

  • We have tissue damage in rheumatoid arthritis because we have antibodies to proteus mirabilis. Rheumatoid arthritis most likely caused by proteus
  • Ankylosing spondylitis caused by a subclinical bowel infection with klebsiella
  • Crohn’s disease caused by subclinical bowel infections with klebsiella

 

VI. MECHANISM FOR INFECTIONS CAUSING AUTOIMMUNE

             RESPONSE

A. Molecular Mimicry

  • The antigen (protein of the virus or bacteria) resembles a part of the human tissues
  • Due to the genetic similarities, the antibodies produced against the infection mistakenly attack body tissues.
  • Examples are:
    • Antigen to proteus mirabilis resembles a specific part of collagen in the hands, feet and parts of the back (associated with rheumatoid arthritis)
    • Antigen to klebsiella pneumonia found in gut (especially with HLA 27) resembles another kind of collagen in the spine
    • Chlamydia pneumonia in lung is very similar to the myelin basic protein
      • 95 % of persons with multiple sclerosis have antibodies against chlamydia pneumonia or a different response to chlamydia

B. Bystander Activator Process

  • They promote inflammatory environment so the body maladapt and makes a mistakes

C. Toxin binding to protein that gets attack

VII. BUGS WHICH CAUSE AUTOIMMUNE REACTIONS

  • Black physic hominus (amoeba parasite)
  • Candida albicans yeast
  • Citrobacter (bacteria)
  • Dientamoeba fragilis parasite
  • Endolimax nana
  • Entamoeba histolytica
  • Giardia
  • H pylori (Hashimotos)
  • enterovirus
    • have at least 2000 viruses in our virome in our gut
    • klebsiella anklyosing spondylitis
    • proteus mirabilis rheumatoid arthritis
    • stephococcus pyogenes psoriasis
    • H pylori for Hashimotos
    • Microplasma pneumonia neurological conditions such as Multiple Sclerosis and transverse myletis
    • chlamydia pneumonia in lung
    • mocroplasm pneumonia to neurological autoimmune disease
      • can end up with lesions in the brain
      • bacteria can produce a lesion in two days
    • Epstein Barr Virus (EBV)
      • For any condition, particularly for Hashimotos and lupus
      • In 1984 was associated with cancer
      • EBV paradox
      • Main driver of autoimmunity especially in tandem with herpes viruses
      • EBV is technically human herpes virus 4
    • Humane Herpes Virus 6
      • most common on earth
      • involved in most autoimmune diseases

VIII. ANTIGEN TESTING

  • The first response is a T cell response
  • Antibodies are an acquired humoural immunity response so body is generating antibodies
  • These antibodies go down long after successful treatment
  • Cyrex Labs for screening antibodies
  • Elisspot test for T cell response
  • IgA , Ig M indicates current infection; can be contagious
  • IgG indicates past exposure: not active not contagious,
  • Most autoimmune diseases have raised IgG
  • this is not benign; it just means not contagious
  • This chronic low grade past exposure still can make antibodies

IX. T CELL RESPONSE TESTING

      ElisSpot Tests (Lymphocyte transformation test

  • Regeneris Laboratory in UK have access
  • Through two German labs
  • Looks at cellular T cell responses (T cell is first response_
  • Can retest to see if activity is reduced.
  • There are 12 bugs that have this test including Epstein Barr Virus, Humane Herpes Virus 6, Shingles, Chlamydia Pneumonia
  • In some patients their antibody levels might be normal, but have a high level on the Elisspot test
  • This does not prove causality
  • So don’t have an antibody response but have a n T cell response.
  • The antibodies might take much longer time to decrease after treatment

X. WHICH BUGS CAUSE A PARTICULAR AUTOIMMUNE DISEASE

  • Rheumatoid arthritis look for
    • proteus mirabilis
  • psoariasis look for
    • streptococcus pyogenes,
    • Epstein Barr Virus (EBV),
    • humane herpes virus Type 6 (HHV 6)
  • ankylosing spondylitis look for
    • klebsiella pneumonia,
    • Epstein Barr Virus (EBV),
    • humane herpes virus Type 6 (HHV)
  • Multiple sclerosis
    • klebsiella pneumonia, ,
    • microplasma pneumonia,
    • EBV,
    • HHV 6
  • Hashimotos Disease look for
    • EBV,
    • HHV 6,
    • H pylori
  • Haynes looks at the infection that is the most likely

XI. TREATMENT

  • Diet
    • What foods to avoid
  • lifestyle
  • Sleep

XII. NATURAL TREATMENTS

A.Supplements having a Direct impact on Infections

Olive leave extract, elderberry, oregano, echinacea, garlic, astragulus, cats claw, ginger, licorice root

B. Anti virals `

Olive leaf extract (allergy research) is his favourite for co supplement

  • More direct effect on viruses

Humic acid (allergy research)

  • strengthens the effects of olive leaf extract
  • 50 – 100k year old fresh water plant turned to compressed compost
  • nano bind to viral bits so can be transferred cell to cell
  • membrane active
  • stronger affinity to bind to viral so cell has strength to next cell
  • Richard Lau believes humic acid inhibits active against all known viruses
  • Passive binding effect to viruses

C. Anti Bacterials

  • Emulsified sustained oregano (biotics) research ADP oregano
    • Chlamydia (can hide from the immune system , micro pneumonia

D  Hertzheimer Reaction

  • Person feels worse as toxins are released from dying viruses and bacteria

E. Support innate immune system

  • 60 – 80 % of the immune cells line gut lining were they have contact with the outside and food
  • more immune decisions are made inside the gut in one day than  are   made in whole of body in a whole lifetime.
  • sacromycis boulardii
    • (Dr Boulard) promotes and support secretory Ig A
    • Supports innate immune system more than any other probiotic
    • Secretory IgA
      • most abundant immunoglobulin 10 x
      • Only immune response that is not inflammatory
      • Not linked to blood IgA
  • Colostrum
  • Vitamin A
  • original name was epithelial nutrient (inner skin)
  • Vitamin D and Vitamin A share the same receptor
  • Excess vitamin D risks creating lesser number vitamin A
  • 40 % Europeans don’t have ability (gene) to convert beta carotene à vitamin A (fat soluble) called retinol
  • cod liver oil unprocessed fish oil
  • want natural form cis form vitamin A
  • liver richest source vitamin A
    • not for pregnant women
  • in full fat butter and full fat dairy products
  • grated carrot with avocado get 5 fold more vitamin A that without the avocado
  • recommends carrot and avocado on Monday, Wednesday, Friday he does not recommend eating the same thing every day.

XIII.  PROTEOLYTIC ENZYMES

  • biotics research in enzyme forte
  • Digestive enzymes away from food
  • reduce inflammation
  • autoimmune can lyse antibody complex in the blood stream
  • breaks down proteins behind which bacteria might be hiding.

XIV  EFFECTS OF ANTI STEROID MEDICATIONS (NSAIDS)

  • impede healing of connective tissue
  • damage the gut lining
  • burden on the liver
  • bad for heart in long term
  • 20,000 hospitalization NSADIs in UK annually
  • 20,000 deaths annually in the US from NSAID

His Recommended Supplements

Olive leaf extract (allergy research) Antiviral

with Humic acid (allergy research) g  filmic inactive

Emulsified oregono  (biotics research)  ADP oregano Antibacterial

research enzyme forte with others Biotics Proteolytic enzymes